The Impact of Timing of Antibiotics on Outcomes in Severe Sepsis and Septic Shock

We sought to systematically review and meta-analyze the available data on the association between timing of antibiotic administration and mortality in severe sepsis and septic shock.A comprehensive search criteria was performed using a predefined protocol.adult patients with severe sepsis or septic shock, reported time to antibiotic administration in relation to emergency department triage and/or shock recognition, and mortality.immunosuppressed...