Preparation of graphene oxide/dendrimer hybrid carriers for delivery of doxorubicin

Hybrid carriers were successfully synthesized by chemically binding OH-terminated fourth generation poly(amido amine) dendrimer and folic acid on graphene oxide (GO) with a size of 100 nm, and their drug carrier ability was compared with hybrids of 1500 nm GO. The small hybrid carriers possessed a 1.3 times lower loading capacity (1.43 g/g(GO)) for doxorubicin (DOX) than the large hybrid carriers. However, the amount (86%) of DOX released at pH...