A literature review of the spatial organization of lamellar bone

Identification and interpretation of bone tissue types is the primary goal of histological analysis. Lamellar bone, a fundamental tissue, is generally easily identifiable in polarized microscopy. It is important, however, to understand the formation and structure of the tissues that are being studied. Lamellae are widely accepted to form a plywood-like structure, but this hypothesis has been and continues to be contested. Here, we discuss the...