Picropodophyllin inhibits proliferation and survival of diffuse large B-cell lymphoma cells
Abstract
Diffuse large B-cell lymphoma (DLBCL) is the most common lymphoma in adults. Although chemotherapy in combination with anti-CD20 antibodies results in a cure rate of 60-70 %, novel treatment approaches are warranted for the remaining patients. The insulin-like growth factor-1 receptor (IGF-1R) and its principal ligands IGF-1 and IGF-2 have been suggested to play pivotal roles in different cancers. However, in DLBCL the importance of this system...
Paper Details
Title
Picropodophyllin inhibits proliferation and survival of diffuse large B-cell lymphoma cells
Published Date
May 29, 2015
Journal
Volume
32
Issue
7
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