Cathepsin G is a strong platelet agonist released by neutrophils.
Abstract
The present studies were undertaken to characterize a serine protease released by N-formyl-L-Met-L-Leu-L-Phe (fMet-Leu-Phe)-stimulated neutrophils that rapidly induces platelet calcium mobilization, secretion and aggregation. The biological activity associated with this protease was unaffected by leupeptin, was only weakly diminished by N-p-tosyl-L-Lys-chloromethane, but was strongly inhibited by alpha 1-antitrypsin, soyabean trypsin inhibitor,...
Paper Details
Title
Cathepsin G is a strong platelet agonist released by neutrophils.
Published Date
Apr 1, 1988
Journal
Volume
251
Issue
1
Pages
293 - 299
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Notes
History