Cardiac Fibrosis Alleviated by Exercise Training Is AMPK-Dependent
Abstract
Regular exercise can protect the heart against external stimuli, but the mechanism is not well understood. We determined the role of adenosine monophosphate-activated protein kinase (AMPK) in regulating swimming exercise-mediated cardiac protection against β-adrenergic receptor overstimulation with isoproterenol (ISO) in mice. Ten-week-old AMPKα2+/+ and AMPKα2-knockout (AMPKα2-/-) littermates were subjected to 4 weeks of swimming training (50...
Paper Details
Title
Cardiac Fibrosis Alleviated by Exercise Training Is AMPK-Dependent
Published Date
Jun 12, 2015
Journal
Volume
10
Issue
6
Pages
e0129971 - e0129971
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