Aldosterone and the Mineralocorticoid Receptor: Risk Factors for Cardiometabolic Disorders
Abstract
Preclinical studies have convincingly demonstrated a role for the mineralocorticoid receptor (MR) in adipose tissue physiology. These studies show that increased MR activation causes adipocyte dysfunction leading to decreased production of insulin-sensitizing products and increased production of inflammatory factors, creating an environment conducive to metabolic and cardiovascular disease. Accumulating data also suggest that MR activation may...
Paper Details
Title
Aldosterone and the Mineralocorticoid Receptor: Risk Factors for Cardiometabolic Disorders
Published Date
Jun 12, 2015
Journal
Volume
17
Issue
7
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