Analysis of epidermal growth factor receptor (EGFR) pathway in oropharyngeal squamous cell cancer patients in vivo (OSCC)

5518 Background: EGFR is important target in OSCC. Dissecting the molecular events associated with activation of this pathway in OSCC patients in vivo presents an important challenge that has implications for the development and clinical testing of EGFR pathway inhibitors. Methods: The cohort was assembled from patients with primary OSCC treated at Yale with external beam radiotherapy (EBRT) or surgery and EBRT. Patients with metastases at...