Original paper
Adiponectin inhibits leptin‐induced cardiomyocyte hypertrophy by attenuation of calcineurin/NFAT activation
Abstract
Leptin and adiponectin are adipokines which exert opposite effects on cardiac pathology. Leptin induces cardiomyocyte hypertrophy and hyperleptinemia has been shown to be a risk factor for developing heart failure. In contrast adiponectin is antihypertrophic and reduced plasma adiponectin levels constitute a cardiovascular risk factor. In the present study we determined whether adiponectin can modify leptin‐induced hypertrophy in cultured rat...
Paper Details
Title
Adiponectin inhibits leptin‐induced cardiomyocyte hypertrophy by attenuation of calcineurin/NFAT activation
Published Date
Apr 1, 2013
Journal
Volume
27
Issue
S1
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Notes
History