Platinum(II) complexes with tris(2-carboxyethyl)phosphine, X-ray structure and reactions with polar solvents and glutathione

It has recently been found that P(C2H4COOH)3 (TCEP), used in the reduction of S–S bonds, promoted reaction of cisplatin with Sp1 zinc finger protein and Cu(I) transporters. However Pt complexes with TCEP were not investigated. New platinum(II) complexes with (TCEP): trans-[PtCl2(TCEP)2] (1) and cis-[PtCl2(TCEP)2]·1.25H2O (2) were fully characterized by IR, 1H, 13C, 31P, 195Pt NMR and ESI-MS spectroscopic techniques. Structures of...