Azo Polymers For Colon Targeted Drug Delivery

Development of a colon specific delivery system bearing flurbiprofen using various azo-aromatic polymers and pH-sensitive polymers are discussed. The azo-aromatic polymers were synthesized and characterized for physical appearance, solubility, film forming properties and effect of colon microbial flora on the polymers. In vitro dissolution studies showed that flurbiprofen bearing hard gelatin capsules, coated with these polymers released drug...