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The biological chemistry of gold

Published on Dec 1, 1976in Gold Bulletin2.279
· DOI :10.1007/BF03215415
Peter J. Sadler92
Estimated H-index: 92
(Birkbeck, University of London)
Abstract
Interest in the effects of gold compounds on biological systems ranges from their use for anti-inflammatory and anti-bacterial purposes to the study of the method of uptake of gold by micro-organisms. By the application of modern physical techniques new light is being shed on the mechanism of action of gold in these areas.
  • References (20)
  • Citations (25)
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Abstract A Bence-Jones protein, Rhe, isolated from the urine of a myeloma patient, has been crystallized. Immunological tests indicate that Rhe contains the constant region of a lambda-type light chain. Gel filtration and sodium dodecyl sulfate gel electrophoresis show that Rhe consists of two subunits, each about half the size of the light chain. Preliminary X-ray crystallographic results and density measurements show that Rhe possesses crystallographic 2-fold symmetry, indicating that the two ...
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Co(II), Cu(II), and Zn(II) complexes of diethylthiourea and dimethylthiourea have been synthesized and characterized by elemental analysis, conductivity, magnetic susceptibility measurements, and FTIR UV-vis spectroscopy. The single-crystal X-ray structure of the Co(II) complex of diethylthiourea, [CoCl2(detu)2], is reported. The metal(II) complexes are four coordinated with two molecules of the alkyl thiourea and two molecules of either chloride or acetate ions. The compounds are nonelectrolyte...
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