Transplantation of gene-modified nucleus pulposus cells reverses rabbit intervertebral disc degeneration.

Volume: 124, Issue: 16, Pages: 2431 - 2437
Published: Aug 1, 2011
Abstract
BACKGROUND: Intervertebral disc degeneration is the main cause of low back pain. The purpose of this study was to explore potential methods for reversing the degeneration of lumbar intervertebral discs by transplantation of gene-modified nucleus pulposus cells into rabbit degenerative lumbar intervertebral discs after transfecting rabbit nucleus pulposus cells with adeno-associated virus 2 (AAV2)-mediated connective tissue growth factor (CTGF)...
Paper Details
Title
Transplantation of gene-modified nucleus pulposus cells reverses rabbit intervertebral disc degeneration.
Published Date
Aug 1, 2011
Volume
124
Issue
16
Pages
2431 - 2437
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