Mitochondrial Metabolism as a Target for Cancer Therapy
Abstract
Recent evidence in humans and mice supports the notion that mitochondrial metabolism is active and necessary for tumor growth. Mitochondrial metabolism supports tumor anabolism by providing key metabolites for macromolecule synthesis and generating oncometabolites to maintain the cancer phenotype. Moreover, there are multiple clinical trials testing the efficacy of inhibiting mitochondrial metabolism as a new cancer therapeutic treatment. In...
Paper Details
Title
Mitochondrial Metabolism as a Target for Cancer Therapy
Published Date
Sep 1, 2020
Journal
Volume
32
Issue
3
Pages
341 - 352
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