Predicting protein stability and solubility changes upon mutations: data perspective
Volume: 12, Issue: 22, Pages: 5590 - 5598
Published: Sep 3, 2020
Abstract
Understanding mutational effects on protein stability and solubility is of particular importance for creating industrially relevant biocatalysts, resolving mechanisms of many human diseases, and producing efficient biopharmaceuticals, to name a few. For in silico predictions, the complexity of the underlying processes and increasing computational capabilities favor the use of machine learning. However, this approach requires sufficient training...
Paper Details
Title
Predicting protein stability and solubility changes upon mutations: data perspective
Published Date
Sep 3, 2020
Volume
12
Issue
22
Pages
5590 - 5598
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