Review paper

Use Chou’s 5-steps rule to identify DNase I hypersensitive sites via dinucleotide property matrix and extreme gradient boosting

Volume: 295, Issue: 6, Pages: 1431 - 1442
Published: Jul 19, 2020
Abstract
DNase I hypersensitive sites (DHSs) are highly sensitive active chromatin regions to DNase I enzymes, which provide the basis for the study of gene transcriptional regulation mechanism and play an important role in the analysis of gene expression regulatory elements. The identification of DHSs has contributed to biomedical research and genome analysis. There are already southern blotting technology and high-throughput sequencing technology to...
Paper Details
Title
Use Chou’s 5-steps rule to identify DNase I hypersensitive sites via dinucleotide property matrix and extreme gradient boosting
Published Date
Jul 19, 2020
Volume
295
Issue
6
Pages
1431 - 1442
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