A critical review of isotopic fractionation and interference correction methods for isotope ratio measurements by laser ablation multi-collector inductively coupled plasma mass spectrometry

Laser ablation multi-collector inductively coupled plasma mass spectrometry (LA-MC-ICP-MS) has become a powerful technique for the in situ direct determination of isotope ratios in various solid materials. Unlike conventional solution analysis, LA-MC-ICP-MS offers analysis with high spatial resolution, high sample throughput, minimal sample preparation, and low contamination. Although the performance of LA-MC-ICP-MS has been improved greatly in...