Copper‐Catalyzed C−H Difluoroalkylation of Coumarins with Fluoroalkyl Bromides

Volume: 12, Issue: 20, Pages: 5256 - 5260
Published: Sep 9, 2020
Abstract
An efficient method for the copper-catalyzed selective C−H difluoroalkylation of coumarins and with low cost and readily available ethyl bromodifluoroacetate and N-phenyl bromodifluoroacetamide has been reported. This reaction exhibits good functional group tolerance with respect to coumarins and difluoroalkylation reagents, and several redox-sensitive substrates have been successfully C−H difluoroalkylated in good to high yield. This design...
Paper Details
Title
Copper‐Catalyzed C−H Difluoroalkylation of Coumarins with Fluoroalkyl Bromides
Published Date
Sep 9, 2020
Journal
Volume
12
Issue
20
Pages
5256 - 5260
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.