Suppression of Netrin-1 attenuates angiotension II-induced cardiac remodeling through the PKC/MAPK signaling pathway

Volume: 130, Pages: 110495 - 110495
Published: Oct 1, 2020
Abstract
Myocardial remodeling caused by angiotensin II (Ang II) is essential for the pathological process of heart failure. Netrin-1, which is an axonal guidance cue, has been shown to be involved in the inflammatory response, tumorigenesis, and angiogenesis in non-neuronal tissues. However, the role of Netrin-1 in cardiac remodeling has not been fully elucidated. The rat cardiomyocyte cell line H9c2 and primary neonatal rat cardiomyocytes were treated...
Paper Details
Title
Suppression of Netrin-1 attenuates angiotension II-induced cardiac remodeling through the PKC/MAPK signaling pathway
Published Date
Oct 1, 2020
Journal
Volume
130
Pages
110495 - 110495
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