Cuminaldehyde induces oxidative stress-mediated physical damage and death of Haemonchus contortus

Cuminaldehyde (CA), a monoterpenoid, preset in many plant sources including cumin, induces reactive oxygen-related damage and death in Haemonchus contortus, a parasitic worm with an LD50, values of 127.3 ± 7.5, 184.5 ± 12.1 and 104.1 ± 7.9 μg/mL for an adult female, adult male worms (12 h) and L3 larvae, respectively (24 h). Fifty percent of inhibition of egg hatching (IC50) was obtained at 142.4 ± 11.4 μg/mL after 48 h of exposure. Scanning...