Parkin is the most common causative gene in a cohort of mainland Chinese patients with sporadic early‐onset Parkinson's disease

Genetic mutations associated with early-onset Parkinson's disease (EOPD) vary widely among different ethnicities. We detected the genes associated with EOPD in a Chinese cohort using next-generation sequencing (NGS) combined with multiplex ligation-dependent probe amplification (MLPA) and analyzed the phenotypic characteristics of the mutation carriers.Cohort of 23 sporadic EOPD patients (onset age ≤ 45 years) were recruited. Genetic causes were...