Regional changes in tuberculosis disease burden among adolescents in South Africa (2005–2015)

Background Adolescents in the Western Cape Province of South Africa had high force of Mycobacterium tuberculosis (MTB) infection (14% per annum) and high TB incidence (710 per 100,000 person–years) in 2005. We describe subsequent temporal changes in adolescent TB disease notification rates for the decade 2005–2015. Method We conducted an analysis of patient–level adolescent (age 10–19 years) TB disease data, obtained from an electronic TB...