The Sca-1+ and Sca-1− mouse prostatic luminal cell lineages are independently sustained

Volume: 38, Issue: 11, Pages: 1479 - 1491
Published: Aug 8, 2020
Abstract
The phenotypic and functional heterogeneity of the mouse prostate epithelial cell lineages remains incompletely characterized. We show that the Sca-1+ luminal cells at the mouse proximal prostate express Sox2. These cells are replicative quiescent, castration resistant, and do not possess secretory function. We use the Probasin-CreERT2 and Sox2-CreERT2 models in concert with a fluorescent reporter line to label the Sca-1- and Sca-1+ luminal...
Paper Details
Title
The Sca-1+ and Sca-1− mouse prostatic luminal cell lineages are independently sustained
Published Date
Aug 8, 2020
Journal
Volume
38
Issue
11
Pages
1479 - 1491
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