Alternative kidney filtration markers and the risk of major macrovascular and microvascular events, and all‐cause mortality in individuals with type 2 diabetes in the ADVANCE trial

Background Creatinine‐based estimated glomerular filtration rate (eGFR) is biased in the setting of obesity and other conditions. Alternative kidney filtration markers may be useful in adults with diabetes, but few studies examined the associations with risk of clinical outcomes. Methods In the Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified Release Controlled Evaluation (ADVANCE) trial, we evaluated whether baseline...