Long-Term Liraglutide Administration Induces Pancreas Neogenesis in Adult T2DM Mice
Abstract
In vivo beta-cell neogenesis may be one way to treat diabetes. We aimed to investigate the effect of glucagon-like peptide-1 (GLP-1) on beta-cell neogenesis in type 2 diabetes mellitus (T2DM). Male C57BL/6J mice, 6 wk old, were randomly divided into three groups: Control, T2DM, and T2DM + Lira. T2DM was induced using high-fat diet and intraperitoneal injection of streptozotocin (40 mg/kg/d for 3 d). At 8 wk after streptozotocin injection, T2DM +...
Paper Details
Title
Long-Term Liraglutide Administration Induces Pancreas Neogenesis in Adult T2DM Mice
Published Date
Jan 1, 2020
Journal
Volume
29
Pages
096368972092739 - 096368972092739
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