A Family of T6SS Antibacterial Effectors Related to l,d-Transpeptidases Targets the Peptidoglycan

Volume: 31, Issue: 12, Pages: 107813 - 107813
Published: Jun 1, 2020
Abstract

Summary

Type VI secretion systems (T6SSs) are nanomachines used by bacteria to inject toxic effectors into competitors. The identity and mechanism of many effectors remain unknown. We characterized a Salmonella T6SS antibacterial effector called Tlde1 that is toxic in target-cell periplasm and is neutralized by its cognate immunity protein (Tldi1). Microscopy analysis reveals that cells expressing Tlde1 stop dividing and lose...
Paper Details
Title
A Family of T6SS Antibacterial Effectors Related to l,d-Transpeptidases Targets the Peptidoglycan
Published Date
Jun 1, 2020
Volume
31
Issue
12
Pages
107813 - 107813
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