Identification of microRNAs and their target gene networks implicated in arterial wall remodelling in giant cell arteritis
Abstract
Objectives To identify dysregulated microRNAs (miRNAs) and their gene targets in temporal arteries from GCA patients, and determine their association with GCA pathogenesis and related arterial wall remodelling. Methods We included 93 formalin-fixed, paraffin-embedded temporal artery biopsies (TABs) from treatment-naïve patients: 54 positive and 17 negative TABs from clinically proven GCA patients, and 22 negative TABs from non-GCA patients....
Paper Details
Title
Identification of microRNAs and their target gene networks implicated in arterial wall remodelling in giant cell arteritis
Published Date
Jun 28, 2020
Journal
Volume
59
Issue
11
Pages
3540 - 3552
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