Disruption of evolutionarily correlated tRNA elements impairs accurate decoding

Volume: 117, Issue: 28, Pages: 16333 - 16338
Published: Jun 29, 2020
Abstract
Significance Accurate gene expression relies on enzymes distinguishing correct from incorrect substrates that are chemically and structurally similar. During protein synthesis, correct base pairing between the tRNA anticodon and the mRNA codon is essential for accurate translation. Other tRNA elements outside of the anticodon also contribute to correct selection by the ribosome, but the structural basis for their contribution to selectivity is...
Paper Details
Title
Disruption of evolutionarily correlated tRNA elements impairs accurate decoding
Published Date
Jun 29, 2020
Volume
117
Issue
28
Pages
16333 - 16338
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