Molecular signature of slowly expanding lesions in progressive multiple sclerosis
Abstract
Multiple sclerosis is an immune-mediated chronic inflammatory disease of the CNS that leads to demyelinated lesions in the grey and white matter. Inflammatory, active demyelinating white matter lesions predominate in the relapsing-remitting disease stages, whereas in the progressive stage the so-called slowly expanding lesion is characteristic. These lesions show an accumulation of macrophages/microglia at their borders, mediating the ongoing...
Paper Details
Title
Molecular signature of slowly expanding lesions in progressive multiple sclerosis
Published Date
Jun 24, 2020
Journal
Volume
143
Issue
7
Pages
2073 - 2088
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