Modifying the tumour microenvironment and reverting tumour cells: New strategies for treating malignant tumours
Abstract
The tumour microenvironment (TME) plays a pivotal role in tumour fate determination. The TME acts together with the genetic material of tumour cells to determine their initiation, metastasis and drug resistance. Stromal cells in the TME promote the growth and metastasis of tumour cells by secreting soluble molecules or exosomes. The abnormal microenvironment reduces immune surveillance and tumour killing. The TME causes low anti-tumour drug...
Paper Details
Title
Modifying the tumour microenvironment and reverting tumour cells: New strategies for treating malignant tumours
Published Date
Jun 26, 2020
Journal
Volume
53
Issue
8
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Notes
History