CRISPR/Cas9 in Male Factor Infertility

Male factor infertility is common and often multifactorial. A subset of these patients have underlying genetic etiologies. CRISPR/Cas9 is a simple and flexible gene editing tool with promising applications in this space. This review aims to summarize the advances that CRISPR/Cas9-based tools have brought to the field and propose future directions for study. CRISPR/Cas9 has been applied successfully to spermatogonial stem cells (SSCs) and via...