Aneuploid cells activate NF-κB to promote their immune clearance by NK cells

Abstract
Summary The immune system plays a major role in the protection against cancer. Identifying and characterizing the pathways mediating this immune surveillance is thus critical for understanding how cancer cells are recognized and eliminated. We previously found that untransformed cells that had undergone senescence due to highly abnormal karyotypes are eliminated by Natural Killer (NK) cells in vitro . Here we show that this is also true for...
Paper Details
Title
Aneuploid cells activate NF-κB to promote their immune clearance by NK cells
Published Date
Jun 27, 2020
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.