An essential role for cardiolipin in the stability and function of the mitochondrial calcium uniporter

Volume: 117, Issue: 28, Pages: 16383 - 16390
Published: Jun 29, 2020
Abstract
Significance The assembly and function of membrane proteins depend on the lipid milieu. In recent years the protein components of the mitochondrial calcium uniporter have been identified, but its specific phospholipid requirements are not known. Utilizing yeast mutants defective in their ability to synthesize different phospholipids, we identify a specific requirement of cardiolipin (CL) in the stability and function of the mitochondrial...
Paper Details
Title
An essential role for cardiolipin in the stability and function of the mitochondrial calcium uniporter
Published Date
Jun 29, 2020
Volume
117
Issue
28
Pages
16383 - 16390
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