Targeted 595‐gene genomic profiling demonstrates low tumor mutational burden in olfactory neuroblastoma

Background Olfactory neuroblastoma (ONB) is a rare skull‐base malignancy associated with delayed local recurrence. Treatment options in recurrent disease are few and unreliable. We undertook analysis of the ONB exome and immune environment in order to identify potential future immunotherapy treatment options. Methods Retrospective chart review and next‐generation targeted 595‐gene genomic profiling was performed on a cohort of 14 ONB cases...