Molecular Characterization of Upper Tract Urothelial Carcinoma in the Era of Next-generation Sequencing: A Systematic Review of the Current Literature

While upper tract urothelial carcinoma (UTUC) share histological appearance with bladder cancer (BC), the former has differences in etiology and clinical phenotype consistent with characteristic molecular alterations. To systematically evaluate current genomic sequencing and proteomic data examining molecular alterations in UTUC. A systematic review using PubMed, Scopus, and Web of Science was performed in December 2019 according to the...