The genomic and epigenomic evolutionary history of papillary renal cell carcinomas
Abstract
Intratumor heterogeneity (ITH) and tumor evolution have been well described for clear cell renal cell carcinomas (ccRCC), but they are less studied for other kidney cancer subtypes. Here we investigate ITH and clonal evolution of papillary renal cell carcinoma (pRCC) and rarer kidney cancer subtypes, integrating whole-genome sequencing and DNA methylation data. In 29 tumors, up to 10 samples from the center to the periphery of each tumor, and...
Paper Details
Title
The genomic and epigenomic evolutionary history of papillary renal cell carcinomas
Published Date
Jun 18, 2020
Journal
Volume
11
Issue
1
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