Molecular Bases of Drug Resistance in Hepatocellular Carcinoma
Abstract
The poor outcome of patients with non-surgically removable advanced hepatocellular carcinoma (HCC), the most frequent type of primary liver cancer, is mainly due to the high refractoriness of this aggressive tumor to classical chemotherapy. Novel pharmacological approaches based on the use of inhibitors of tyrosine kinases (TKIs), mainly sorafenib and regorafenib, have provided only a modest prolongation of the overall survival in these HCC...
Paper Details
Title
Molecular Bases of Drug Resistance in Hepatocellular Carcinoma
Published Date
Jun 23, 2020
Journal
Volume
12
Issue
6
Pages
1663 - 1663
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Notes
History