Lipids, inflammasomes, metabolism, and disease
Abstract
Inflammasomes are multi-protein complexes that regulate the cleavage of cysteine protease caspase-1, secretion of inflammatory cytokines, and induction of inflammatory cell death, pyroptosis. Several members of the nod-like receptor family assemble inflammasome in response to specific ligands. An exception to this is the NLRP3 inflammasome which is activated by structurally diverse entities. Recent studies have suggested that NLRP3 might be a...
Paper Details
Title
Lipids, inflammasomes, metabolism, and disease
Published Date
Jun 20, 2020
Journal
Volume
297
Issue
1
Pages
108 - 122
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Notes
History