Targeting the Hippo pathway in cancer, fibrosis, wound healing and regenerative medicine

Volume: 19, Issue: 7, Pages: 480 - 494
Published: Jun 17, 2020
Abstract
The Hippo pathway is an evolutionarily conserved signalling pathway with key roles in organ development, epithelial homeostasis, tissue regeneration, wound healing and immune modulation. Many of these roles are mediated by the transcriptional effectors YAP and TAZ, which direct gene expression via control of the TEAD family of transcription factors. Dysregulated Hippo pathway and YAP/TAZ–TEAD activity is associated with various diseases, most...
Paper Details
Title
Targeting the Hippo pathway in cancer, fibrosis, wound healing and regenerative medicine
Published Date
Jun 17, 2020
Volume
19
Issue
7
Pages
480 - 494
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