Reconciling protective and pathogenic roles of the NLRP3 inflammasome in leishmaniasis
Abstract
Leishmaniasis is a global health problem that affects more than 2 billion people worldwide. Recent advances in research have demonstrated critical roles for cytoplasmic sensors and inflammasomes during Leishmania spp. infection and pathogenesis. Specifically, several studies have focused on the role of nod-like receptor family, pyrin domain-containing protein 3 (NLRP3) inflammasome and inflammasome-associated cytokines IL-1β and IL-18 in...
Paper Details
Title
Reconciling protective and pathogenic roles of the NLRP3 inflammasome in leishmaniasis
Published Date
Jun 20, 2020
Journal
Volume
297
Issue
1
Pages
53 - 66
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