Cortical neurons derived from human pluripotent stem cells lacking FMRP display altered spontaneous firing patterns
Abstract
Fragile X syndrome (FXS), a neurodevelopmental disorder, is a leading monogenetic cause of intellectual disability and autism spectrum disorder. Notwithstanding the extensive studies using rodent and other pre-clinical models of FXS, which have provided detailed mechanistic insights into the pathophysiology of this disorder, it is only relatively recently that human stem cell-derived neurons have been employed as a model system to further our...
Paper Details
Title
Cortical neurons derived from human pluripotent stem cells lacking FMRP display altered spontaneous firing patterns
Published Date
Jun 19, 2020
Journal
Volume
11
Issue
1
Pages
1 - 16
Citation AnalysisPro
You’ll need to upgrade your plan to Pro
Looking to understand the true influence of a researcher’s work across journals & affiliations?
- Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
- Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.
Notes
History