Crystal Structure of Exotoxin A from Aeromonas Pathogenic Species
Abstract
Aeromonas exotoxin A (AE) is a bacterial virulence factor recently discovered in a clinical case of necrotising fasciitis caused by the flesh-eating Aeromonas hydrophila. Here, database mining shows that AE is present in the genome of several emerging Aeromonas pathogenic species. The X-ray crystal structure of AE was solved at 2.3 Å and presents all the hallmarks common to diphthamide-specific mono-ADP-ribosylating toxins, suggesting AE is a...
Paper Details
Title
Crystal Structure of Exotoxin A from Aeromonas Pathogenic Species
Published Date
Jun 15, 2020
Journal
Volume
12
Issue
6
Pages
397 - 397
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