Perinatal fluoxetine exposure disrupts the circadian response to a phase-shifting challenge in female rats

Volume: 237, Issue: 8, Pages: 2555 - 2568
Published: Jun 12, 2020
Abstract
Rationale Selective serotonin reuptake inhibitor (SSRI) antidepressants are increasingly prescribed during pregnancy. Changes in serotonergic signaling during human fetal development have been associated with changes in brain development and with changes in affective behavior in adulthood. The suprachiasmatic nucleus (SCN) is known to be modulated by serotonin and it is therefore assumed that SSRIs may affect circadian rhythms. However, effects...
Paper Details
Title
Perinatal fluoxetine exposure disrupts the circadian response to a phase-shifting challenge in female rats
Published Date
Jun 12, 2020
Volume
237
Issue
8
Pages
2555 - 2568
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