Clonal hematopoiesis is associated with adverse outcomes in multiple myeloma patients undergoing transplant
Abstract
Multiple myeloma (MM) is a plasma-cell neoplasm that is treated with high-dose chemotherapy, autologous stem cell transplant (ASCT) and long-term immunomodulatory drug (IMiD) maintenance. The presence of somatic mutations in the peripheral blood is termed clonal hematopoiesis of indeterminate potential (CHIP) and is associated with adverse outcomes. Targeted sequencing of the stem cell product from 629 MM patients treated by ASCT at the...
Paper Details
Title
Clonal hematopoiesis is associated with adverse outcomes in multiple myeloma patients undergoing transplant
Published Date
Jun 12, 2020
Journal
Volume
11
Issue
1
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