Janus nanoparticles with asymmetrically subcompartmentalized sensing and amplification modules toward fluorescence detection of microRNA

Volume: 320, Pages: 128438 - 128438
Published: Oct 1, 2020
Abstract
The design and interfacial engineering of DNA functionalized nanosensors with spatially separated but functionally integrated detection units holds a great promise in optical biosensors. In this study, we developed a bi-component hybrid of Janus nanoquencher particles with immobilized enzymes for fluorescence-based “off-on” detection in solution. Specifically, the hybrids consisting of a mesoporous polydopamine nanoparticle (MPDA) side (∼200 nm)...
Paper Details
Title
Janus nanoparticles with asymmetrically subcompartmentalized sensing and amplification modules toward fluorescence detection of microRNA
Published Date
Oct 1, 2020
Volume
320
Pages
128438 - 128438
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