Study of the Ability of Lutein and Neoxanthin as Standards and in the Extract of Chlamydomonas reinhardtii to Prevent Oxidatively Induced DNA Base Damage Using Ultrasensitive GC–MS/MS Analysis

In this study, two carotenoid antioxidants lutein and neoxanthin were investigated for their ability to prevent oxidatively induced DNA damage. A Chlamydomonas reinhardtii alga was used as the natural source of lutein and neoxanthin. Analysis using HPLC with Diode Array Detector (DAD) showed that lutein and neoxanthin were the most abundant carotenoids in the extract of C. reinhardtii. An analysis using GC–MS/MS was performed to measure the...