Human Pluripotent Stem Cell-Derived Organoids as Models of Liver Disease
Abstract
Background & AimsThere are few in vitro models for studying the 3-dimensional interactions among different liver cell types during organogenesis or disease development. We aimed to generate hepatic organoids that comprise different parenchymal liver cell types and have structural features of the liver, using human pluripotent stem cells.MethodsWe cultured H1 human embryonic stem cells (WA-01, passage 27-40) and induced pluripotent stem cells...
Paper Details
Title
Human Pluripotent Stem Cell-Derived Organoids as Models of Liver Disease
Published Date
Oct 1, 2020
Journal
Volume
159
Issue
4
Pages
1471 - 1486.e12
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