Plasticity and Spontaneous Activity Pulses in Disused Human Brain Circuits
Abstract
To induce brain plasticity in humans, we casted the dominant upper extremity for 2 weeks and tracked changes in functional connectivity using daily 30-min scans of resting-state functional MRI (rs-fMRI). Casting caused cortical and cerebellar regions controlling the disused extremity to functionally disconnect from the rest of the somatomotor system, while internal connectivity within the disused sub-circuit was maintained. Functional...
Paper Details
Title
Plasticity and Spontaneous Activity Pulses in Disused Human Brain Circuits
Published Date
Aug 1, 2020
Journal
Volume
107
Issue
3
Pages
580 - 589.e6
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History