The effects of antiepileptic drugs on high-frequency oscillations in somatosensory evoked potentials

High frequency oscillations (HFOs) of Somatosensory evoked potentials (SEPs) reflect the activity of thalamo-cortical and cortical neurons from the sensory pathway. Antiepileptic-drugs (AEDs) reduce seizures acting on the balance between excitation and inhibition. We aimed to study the effect of AED mono and polytherapy on SEP-HFO’s components. Twenty-five patients with focal epilepsy were enrolled for the purpose of this study. Patients were...