A Feedforward Loop within the Thyroid-Brown Fat Axis Facilitates Thermoregulation

Lijuan Sun; Hui Jen Goh; Priya Govindharajulu; Lei Sun; Christiani Jeyakumar Henry; Melvin Khee-Shing Leow

doi:https://doi.org/10.1038/s41598-020-66697-0

doi.org/10.1038/s41598-020-66697-0

A Feedforward Loop within the Thyroid-Brown Fat Axis Facilitates Thermoregulation

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..., Melvin Khee-Shing Leow

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Scientific Reports4.60

Volume: 10, Issue: 1

Published: Jun 15, 2020

Abstract

Thyroid hormones (TH) control brown adipose tissue (BAT) activation and differentiation, but their subsequent homeostatic response following BAT activation remains obscure. This study aimed to investigate the relationship between cold- and capsinoids-induced BAT activation and TH changes between baseline and 2 hours post-intervention. Nineteen healthy subjects underwent 18 F-fluorodeoxyglucose positron-emission tomography ( 18 F-FDG PET) and...

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Paper Details

Title

A Feedforward Loop within the Thyroid-Brown Fat Axis Facilitates Thermoregulation

DOI

doi.org/10.1038/s41598-020-66697-0

Published Date

Jun 15, 2020

Journal

Scientific Reports

Volume

10

Issue

1

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